Leave Pisa airport from the exit adjacent to the car rental parking depot and turn
right in the direction signposted Firenze. Follow this road (a dual carriageway)
all the way to Firenze. You will eventually, just outside Firenze, come to a signpost
for the Autostrada A1 and Roma. Take this turning. Follow the exit off the road and
round a bend to the right, you will come to a junction with a tollbooth for the Autostrada
ahead of you. Go onto the Autostrada in the direction of Roma, turning off at the
Val di Chiana exit following the directions as for Rome.